Digestive and Metabolic Diseases

Inflammatory Bowel Disease and Intestinal Inflammation

Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is characterized by chronic inflammation of the gastrointestinal tract. While the exact cause remains unclear, a combination of genetic susceptibility, immune dysregulation, environmental triggers, and microbial imbalance is implicated.

This session focuses on the evolving landscape of IBD pathogenesis, diagnostic biomarkers, and treatment strategies. It includes conventional therapies like aminosalicylates, corticosteroids, and immunosuppressants, as well as biologics targeting tumor necrosis factor-alpha, integrins, and interleukins. Emerging therapies like small molecules (JAK inhibitors) and microbiome modulation also offer hope.

Advances in imaging, endoscopic assessment, and personalized medicine are improving disease monitoring and patient outcomes.

Key Topics:

• Crohn’s disease and ulcerative colitis

• Genetic and environmental factors

• Immune system dysregulation

• Biologics and small molecule therapies

• Diagnostic biomarkers and imaging

• Nutritional support in IBD

• Microbiome-immune interactions